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Haematological, blood sugar, and body mass index changes in Sprague-Dawley rats administered with wa

Authors: EHICHIOYA David

Publication Type: Journal article

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Background: Watermelon [Citrullus lanatus, (Cucurbitaceae)] has been reported to have many potentially bioactive compounds proven to improve health. Aim: This study determined the outcome of watermelon juice on BMI, blood sugar, and haematological parameters in Sprague-Dawley female rats. Methods: A total number of 18 adult rats were used. Animals were randomly divided into three groups: A (control), B (0.5 ml of watermelon juice) and C (1.0 ml of watermelon juice). Watermelon was orally administered daily for 30 days. Haematological analysis was carried by using Beckman-coulter haematological analyzer and CD4+ Dynal bead technique. Glucose concentration was determined after enzymatic oxidation and BMI calculated using rat weights and lengths. Results: In group C, there was a significant reduction in BMI compared to group A (1.08 Â± 0.04) (P<0.05) even though blood sugar level across the three groups was within same range. CD4+ count was significantly increased in group C (8.67 Â± 0.88) (P<0.05) compared to the control group (5.00 Â± 1.15) and WBC increased marginally in both treatment groups after 30 days of ingesting the watermelon juice. NEUT and PLT increased slightly in group C compared to control group. RBC, HCT and HGB concentrations from the experimental rats in groups B and C were similar but reduced slightly compared to group A. Conclusion: Consumption of watermelon juice led to reduced body weight gain and maintained a relative blood sugar level. It may suggest ability to provide vital nutrients, stop bleeding, fight microbial infections and possible initiation of immune response.

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EHICHIOYA,D. . (0000). Haematological, blood sugar, and body mass index changes in Sprague-Dawley rats administered with wa, 0 (), 0-0.

EHICHIOYA,D. . "Haematological, blood sugar, and body mass index changes in Sprague-Dawley rats administered with wa" 0, no (), (0000): 0-0.

EHICHIOYA,D. and . (0000). Haematological, blood sugar, and body mass index changes in Sprague-Dawley rats administered with wa, 0 (), pp0-0.

EHICHIOYAD, . Haematological, blood sugar, and body mass index changes in Sprague-Dawley rats administered with wa. 0000, 0 ():0-0.

EHICHIOYA,David , . "Haematological, blood sugar, and body mass index changes in Sprague-Dawley rats administered with wa", 0 . (0000) : 0-0.

E.David , "Haematological, blood sugar, and body mass index changes in Sprague-Dawley rats administered with wa" vol.0, no., pp. 0-0, 0000.

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