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Chemical constituents in n-butanol fractions of Costus afer Ker Gawl leaf and stem.

Authors: ANYASOR Godswill , Onajobi Funmilayo , Osilesi Odutola , Adebawo , Oboutor Efere

Publication Type: Journal article

Journal: Journal Of Intercultural Ethnopharmacology

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Abstract

Aim: This study was designed to investigate the bioactive compounds in Costus afer Ker Gawl, an indigenous
African medicinal plant whose leaf and stem extracts are used in the treatment of chronic inflammatory
diseases, especially rheumatism and arthritis. Materials and Methods: The bioactive compounds present
in the n-butanol fractions of C. afer leaf and stem were identified using qualitative phytochemical evaluation
and gas chromatography-mass spectrometry (GC/MS) analytical method, comparing the mass spectra of
the identified compounds with those of the National Institute of Standards and Technology database library.
Results: Qualitative analysis detected alkaloids, saponins, diterpenes, triterpenes, phytosterol, phlobatannins,
and tannins in both n-butanol fractions of C. afer leaf and stem. Phenols were detected in leaves alone
while flavonoids were present in stem alone. GC/MS data showed that the bioactive compounds in n-butanol
fraction of C. afer leaf were indolizine, 2-methoxy-4 vinylphenol, phytol, hexadecanoic acid-methyl ester,
n-hexadecanoic acid, 9,12-octadecanoic acid-methyl ester, eicosane, cis-vaccenic acid and oleic acid while
n-butanol fraction of C. afer stem contain benzofuran,2,3-dihydro,2-methoxy-4 vinylphenol, 9-octadecenoic
acid (Z)-2-hydroxy-1-(hydroxymethyl) ethyl ester, campesterol, stigmasterol, hexadecanoic acid-methyl ester,
n-hexadecanoic acid, and cis-vaccenic acid. Conclusion: The bioactive compounds identified in the n-butanol
fractions of C. afer leaves and stem may explain the folkloric use of C. afer plant in the treatment of chronic
inflammatory and oxidative stress related diseases.

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ANYASOR,G. Onajobi,F. Osilesi,O. Adebawo,O. Oboutor,E. . (2014). Chemical constituents in n-butanol fractions of Costus afer Ker Gawl leaf and stem., 3 (), 78-78.

ANYASOR,G. Onajobi,F. Osilesi,O. Adebawo,O. Oboutor,E. . "Chemical constituents in n-butanol fractions of Costus afer Ker Gawl leaf and stem." 3, no (), (2014): 78-78.

ANYASOR,G. and Onajobi,F. and Osilesi,O. and Adebawo,O. and Oboutor,E. and . (2014). Chemical constituents in n-butanol fractions of Costus afer Ker Gawl leaf and stem., 3 (), pp78-78.

ANYASORG, OnajobiF, OsilesiO, AdebawoO, OboutorE, . Chemical constituents in n-butanol fractions of Costus afer Ker Gawl leaf and stem.. 2014, 3 ():78-78.

ANYASOR,Godswill , Onajobi,Funmilayo , Osilesi,Odutola , Adebawo,Olugbenga , and Oboutor,Efere . "Chemical constituents in n-butanol fractions of Costus afer Ker Gawl leaf and stem.", 3 . (2014) : 78-78.

[1] A.Godswill O.Funmilayo O.Odutola A.Olugbenga & O.Efere , "Chemical constituents in n-butanol fractions of Costus afer Ker Gawl leaf and stem." vol.3, no., pp. 78-78, 2014.

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