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In vitro antioxidant activities of ethanolic extract and triterpenoid fraction of Garcinia kola stem bark and inhibition of arsenic-induced rat liver and kidney mitochondrial membrane permeability transition.

Authors: ANYASOR Godswill , Adesola J. Ajagunna

Publication Type: Journal article

Journal: International Journal Of Advanced Research

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Abstract

This study was designed to investigate the in vitro antioxidant activities and inhibitory effects of G. kola stem bark ethanolic extract (EEGK) and triterpenoid fraction (TFGK) on arsenic-induced liver and kidney mitochondrial membrane permeability transitions (MMPTs). DPPH (1-1-diphenyl 2-picryl hydrazyl), hydrogen peroxide scavenging (HPSA), hydroxyl radical scavenging (HRSA) and total antioxidant capacity (TAC) assays were performed to determine antioxidant activity in vitro. Rat liver and kidney mitochondrial fractions were isolated using differential centrifugation technique while MMPT assay was performed using spectrophotometric method. Results showed that EEGK had a significantly (P<0>

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ANYASOR,G. Adesola,J.A . (2017). In vitro antioxidant activities of ethanolic extract and triterpenoid fraction of Garcinia kola stem bark and inhibition of arsenic-induced rat liver and kidney mitochondrial membrane permeability transition., 5 (), 724-724.

ANYASOR,G. Adesola,J.A . "In vitro antioxidant activities of ethanolic extract and triterpenoid fraction of Garcinia kola stem bark and inhibition of arsenic-induced rat liver and kidney mitochondrial membrane permeability transition." 5, no (), (2017): 724-724.

ANYASOR,G. and Adesola,J.A and . (2017). In vitro antioxidant activities of ethanolic extract and triterpenoid fraction of Garcinia kola stem bark and inhibition of arsenic-induced rat liver and kidney mitochondrial membrane permeability transition., 5 (), pp724-724.

ANYASORG, AdesolaJA, . In vitro antioxidant activities of ethanolic extract and triterpenoid fraction of Garcinia kola stem bark and inhibition of arsenic-induced rat liver and kidney mitochondrial membrane permeability transition.. 2017, 5 ():724-724.

ANYASOR,Godswill , and Adesola,J. Ajagunna . "In vitro antioxidant activities of ethanolic extract and triterpenoid fraction of Garcinia kola stem bark and inhibition of arsenic-induced rat liver and kidney mitochondrial membrane permeability transition.", 5 . (2017) : 724-724.

[1] A.Godswill & A.J. Ajagunna , "In vitro antioxidant activities of ethanolic extract and triterpenoid fraction of Garcinia kola stem bark and inhibition of arsenic-induced rat liver and kidney mitochondrial membrane permeability transition." vol.5, no., pp. 724-724, 2017.

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