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Chemical analysis and protective effect of Elaeis guineensis kernel oil against calcium ion-induced mitochondrial membrane permeability transition.

Authors: ANYASOR Godswill , Onuoha, Elizabeth, Gisarin Olusola

Publication Type: Journal article

Journal: Journal Of Basic And Applied Research

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Abstract

This study evaluated the chemical property and effect of Elaeis guineensis kernel (EGK) oil on calcium ion-induced mitochondrial membrane permeability transition (MMPT) using standard in vitro methods. Results showed the EGK oil values for iodine (46.53±1.8 Wij’s), saponification (246.33±1.2 mgKOH/g), acid (10.32±2.5%) and peroxide (3.03±0.4 mEq/kg). EGK oil (150 ?g/ml) exhibited a maximal inhibitory (80.9±4.8%) effect on MMPT. Furthermore, EGK oil (100 ?g/ml) maximally stabilized (96.72±5.2%) erythrocyte membrane against hypotonicity-induced hemolysis. In addition, EGK oil (250 ?g/ml) inhibited heat-induced protein denaturation by 12.42±2.6% and mitochondria lipid peroxidation by 61.03±3.7%. This study showed that EGK oil could possess mitochondria protective agent(s).

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ANYASOR,G. Onuoha,,E.E Gisarin,O. . (2016). Chemical analysis and protective effect of Elaeis guineensis kernel oil against calcium ion-induced mitochondrial membrane permeability transition., 2 (), 140-140.

ANYASOR,G. Onuoha,,E.E Gisarin,O. . "Chemical analysis and protective effect of Elaeis guineensis kernel oil against calcium ion-induced mitochondrial membrane permeability transition." 2, no (), (2016): 140-140.

ANYASOR,G. and Onuoha,,E.E and Gisarin,O. and . (2016). Chemical analysis and protective effect of Elaeis guineensis kernel oil against calcium ion-induced mitochondrial membrane permeability transition., 2 (), pp140-140.

ANYASORG, Onuoha,EE, GisarinO, . Chemical analysis and protective effect of Elaeis guineensis kernel oil against calcium ion-induced mitochondrial membrane permeability transition.. 2016, 2 ():140-140.

ANYASOR,Godswill , Onuoha,,Ezinwanne Elizabeth, and Gisarin,Olusola . "Chemical analysis and protective effect of Elaeis guineensis kernel oil against calcium ion-induced mitochondrial membrane permeability transition.", 2 . (2016) : 140-140.

[1] A.Godswill O.Ezinwanne Elizabeth & G.Olusola , "Chemical analysis and protective effect of Elaeis guineensis kernel oil against calcium ion-induced mitochondrial membrane permeability transition." vol.2, no., pp. 140-140, 2016.

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