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Candidiasis in HIV Positive Female Adults on HAART in Ogun State, Nigeria: Prevalence, Risk Factors and Antifungal Susceptibility Study

Authors: ENITAN Samson

Publication Type: Journal article

Journal: Arc Journal Of Aids

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Abstract

Background: Candidiasis is the most common opportunistic fungal infection reported in human immunodeficiency virus (HIV) positive patients worldwide. Aim: This study was designed to investigate the prevalence of Candida colonization in the mouth and vagina of HIV seropositive adult females on highly active antiretroviral therapy (HAART) in Ogun State, Nigeria, as well as to determine the antifungal susceptibility pattern of the Candida isolates. Methods: A total of one hundred and twenty (120) consenting HIV positive female patients on HAART were recruited for the study. Oral and vagina swabs were collected in duplicates from the participants and streaked on Sabouraud's Dextrose Agar (SDA) plates. Identification of Candida species was performed by conventional methods, while the antifungal susceptibility testing of the yeast isolates was performed using the disc diffusion method with commercially produced antifungal discs. Data were analyzed using Statistical Package for Social Scientist version 18.0 (SPSS-18.0). Results: Out of the 120 participants examined, 60 (50%) of them were colonized by Candida yeasts. 10.8% were positive for only oral candidiasis, 21.7% were positive for only vaginal candidiasis, whereas 17.5% were positive for both oral and vaginal candidiasis. Percentage co-occurrence of oral and vaginal candidiasis was found to be significantly higher (P<0>

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ENITAN,S. . (2019). Candidiasis in HIV Positive Female Adults on HAART in Ogun State, Nigeria: Prevalence, Risk Factors and Antifungal Susceptibility Study, 4 (), 1-1.

ENITAN,S. . "Candidiasis in HIV Positive Female Adults on HAART in Ogun State, Nigeria: Prevalence, Risk Factors and Antifungal Susceptibility Study" 4, no (), (2019): 1-1.

ENITAN,S. and . (2019). Candidiasis in HIV Positive Female Adults on HAART in Ogun State, Nigeria: Prevalence, Risk Factors and Antifungal Susceptibility Study, 4 (), pp1-1.

ENITANS, . Candidiasis in HIV Positive Female Adults on HAART in Ogun State, Nigeria: Prevalence, Risk Factors and Antifungal Susceptibility Study. 2019, 4 ():1-1.

ENITAN,Samson , . "Candidiasis in HIV Positive Female Adults on HAART in Ogun State, Nigeria: Prevalence, Risk Factors and Antifungal Susceptibility Study", 4 . (2019) : 1-1.

E.Samson , "Candidiasis in HIV Positive Female Adults on HAART in Ogun State, Nigeria: Prevalence, Risk Factors and Antifungal Susceptibility Study" vol.4, no., pp. 1-1, 2019.

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