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Comparative study of the effects of the effects of different fractions of Ficus exasperata Vahl. on mitochondria membrane permeability transition pore.

Authors: ANYASOR Godswill

Publication Type: Journal article

Journal: Ira International Journal Of Applied Science

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Abstract

A number of phytochemicals have been established as potent inducers of the mitochondrial membrane permeability transition (MMPT) pore, a transient structure formed in the inner mitochondrial membrane (IMM). There is however no information on the effect of Ficus exasperata (F. exasperata) a popular medicinal plant, on this pore, necessitating this investigation. The in vitro effects of varying concentrations (200, 400, 600, 800 and 1000?g/ml) of the methanol, n-hexane and ethylacetate fractions of leaf and stem of F. exasperata on MMPT pore opening in experimental rat liver were assessed. Opening of MMPT pore was spectrophotometrically assayed under succinate-energized condition using a modified method of Lapidus and Sokolove, 1993[34]. The results obtained for the Stem Methanol Fraction (SMF) and Leaf Methanol Fraction (LMF) show significant (P< 0>

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ANYASOR,G. . (2018). Comparative study of the effects of the effects of different fractions of Ficus exasperata Vahl. on mitochondria membrane permeability transition pore., 12 (), 15-15.

ANYASOR,G. . "Comparative study of the effects of the effects of different fractions of Ficus exasperata Vahl. on mitochondria membrane permeability transition pore." 12, no (), (2018): 15-15.

ANYASOR,G. and . (2018). Comparative study of the effects of the effects of different fractions of Ficus exasperata Vahl. on mitochondria membrane permeability transition pore., 12 (), pp15-15.

ANYASORG, . Comparative study of the effects of the effects of different fractions of Ficus exasperata Vahl. on mitochondria membrane permeability transition pore.. 2018, 12 ():15-15.

ANYASOR,Godswill , . "Comparative study of the effects of the effects of different fractions of Ficus exasperata Vahl. on mitochondria membrane permeability transition pore.", 12 . (2018) : 15-15.

[1] A.Godswill , "Comparative study of the effects of the effects of different fractions of Ficus exasperata Vahl. on mitochondria membrane permeability transition pore." vol.12, no., pp. 15-15, 2018.

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